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Beyond cancer biology, DES(1-3) IGF-1 has been investigated in neuroprotection models, where its high potency and reduced IGFBP binding facilitate clean receptor activation in brain tissue preparations where IGFBP concentrations would otherwise limit native IGF-1 activity

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This finding indicated a profound impairment of ATP production, reflected by decreases in the OCR-linked ATP levels ( Figures 2A, C )

Some diseases and ageing may be caused by free radicals

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